Zmax

  • Update(12/7/2018)
  • PURPOSE:R package for a robust and powerful approach for association analysis on X chromosome based on case-control data, which takes account of different dosage compensation patterns. Moreover, it requires neither specifying the underlying genetic models nor the assumption of Hardy-Weinberg equilibrium.
  • NOTE: This package was built on R (version 3.5.1 with 64-bit). Users should install and use the package under the R (version 3.5.1 with 64-bit) environment. The Zmax package will use the R package "mvtnorm". Therefore, make sure that this package has been installed and loaded into R.
  • Complied R package file for Windows (in a zipped file): Zmax_0.1.0.zip
  • Complied R package file for Linux and Unix (in a zipped, tar file): Zmax_0.1.0.tar.gz
  • Instructions: Instructions.txt

References:

[1] Peng Wang, Si-Qi Xu, Bei-Qi Wang, Wing Kam Fung and Ji-Yuan Zhou. 2018 A Robust and Powerful Test for Case-Control Genetic Association Study on X Chromosome. (submitted)